S'pore scientists identify genes for central corneal thickness

SINGAPORE: Singapore scientists have identified genes for central corneal thickness (CCT) that may cause potentially blinding eye conditions. These eye conditions include glaucoma, as well as the progressive thinning of the cornea, which may eventually lead to a need for corneal transplantation.

The team is from the Singapore Eye Research Institute and the Genome Institute of Singapore, which is an institute of the Agency for Science, Technology and Research (A*STAR).

A*STAR has described the findings as a world first. It said they show that Singapore is well placed globally in eye and genetics research in finding causes for sight threatening conditions.

Eye doctors can use genetic analysis to better manage such patients and prevent their condition from getting worse.

The team studied 55 hospitals and research centres around the world and analysed more than 20,000 individuals in European and Asian populations.

CCT is linked to potentially blinding eye conditions such as keratoconus, a condition where the cornea progressively thins and takes on a more conical shape that may eventually require transplantation.

A*STAR said the Singapore team has had remarkable success identifying the most CCT-associated loci to date.

It identified six distinct genetic loci in two papers published in 2011 and 2012 via samples collected from Singaporean Chinese, Indians, and Malays, as well as Chinese in Beijing. However, none was found to be associated with common eye diseases like this study has now shown.

Overall, this new study identified a total of 27 associated loci, including six for the keratoconus. These observations suggest that most of the CCT-associated loci identified from populations of European descent are shared with Asian populations.

-CNA/ac

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Chelsea Clinton: Make a difference

First lady Michelle Obama helps paint a bench at a service event. She and her family will be participating in National Service Day.

STORY HIGHLIGHTS

• Chelsea Clinton heads National Day of Service on Saturday, will kick off inauguration weekend


• All the states will offer volunteer opportunities everyone can participate in, she writes


• Chelsea Clinton's grandmothers instilled in her family the value of service


• She says if everyone commits to year-round volunteer work, lots can be achieved

Editor's note: Chelsea Clinton works with the Clinton Foundation and the Clinton Global Initiative and serves on the boards of both organizations. She is a special correspondent for NBC News and also serves on the boards of the School of American Ballet, Common Sense Media and the Weill Cornell Medical College. She and her husband, Marc, live in New York City.

(CNN) -- I'm proud to be the honorary chair of the National Day of Service happening this Saturday, inspired by Martin Luther King Jr.'s life and legacy. It's the perfect way to kick off the inauguration weekend because anyone can participate, and we know that when we work together, we will achieve more than one person could on his or her own.

President Barack Obama, Vice President Joe Biden, members of Congress and their families will be rolling up their sleeves at service projects in our nation's capital. But you don't have to be in Washington to get involved. From repairing fire-damaged homes in Colorado and cleaning sidewalks in Detroit to spending time with children with disabilities in New Orleans, every state will offer opportunities to volunteer.

All these projects have one big thing in common: They're making a community, our country and our world better. That's part of what makes service special. Whether it's volunteering time, skills, ideas or resources, we all can make a difference.

Chelsea Clinton

When I was growing up, my parents and grandparents taught me that engaging in service, helping our neighbors and building strong communities are all part of being a good citizen and a good person.

My grandmothers, Virginia and Dorothy, embodied that conviction.

They both had hard lives growing up during the Depression and World War II, but despite the obstacles they faced, they found time to volunteer at their churches and community centers and later, their kids' schools. They created families full of love, support and service.

My parents instilled their mothers' values in me from early on. In Little Rock, Arkansas, we went to church on Sundays, and afterward, conversation often turned to what volunteer project we could do together. Favorites were deciding which books to donate to the church or library and cleaning up parks together, something my father always managed turn into a game.

When we moved to Washington, service remained an important part of my life. In high school, I helped head the service club, and in college, I volunteered as an America Reads tutor and in the art therapy room at the Lucile Packard Children's Hospital in California. I loved talking to my grandmothers about my volunteer work, and I agreed with them: I received more than I could ever possibly give.

Some volunteer work, such as removing debris after hurricanes, is undeniably hard, physically and emotionally. But a lot of activities, such as chaperoning school field trips, helping a sick child make a collage, reading to older people who have lost their eyesight or participating in an AIDS walk with friends, can be lots of fun. The work is also elevating and powerful.

This Saturday, as I join thousands of Americans coming together to do their part, I'll be thinking about my grandmothers, just like I do every day. I know they'd be proud of our country, that in cities and towns across America, people are lending their neighbors a hand, just as they taught their children and grandchildren to do.

But as exciting as the National Day of Service will be, it will be even more powerful if it is just the beginning. Already, people are going online to pledge to make giving back a part of their lives, not just for a day or for a week, but all year round. If everyone who pitches in this weekend keeps up that commitment throughout the year, think about how much good we can all do. Lots of small acts add up to big change.

Nineteen years ago, my father proudly signed the bill making Martin Luther King Day a time dedicated to serving others. At the speech he gave to mark the event, he reminded us of what King once called, "Life's most persistent and urgent question: What are you doing for others?"

There are countless right answers to that question -- the only wrong one is to do nothing. As we think about the future of our communities and our country, we each have the ability and the responsibility to participate.

I hope you can join me, the first family and our entire American family this Saturday as we make this country that we love even better. You can learn more, find an event near you, and pledge to serve here, at the National Day of Service site.

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The opinions expressed in this commentary are solely those of Chelsea Clinton.

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Aurora massacre theater reopening: report

AURORA, Colo. A Colorado movie theater where 12 people were killed and dozens were injured is reopening, The Denver Post reports.

On Tuesday and Wednesday, victims and their families will be allowed to tour the complex, now known as Century Aurora, which has undergone months of remodeling.

The complex will officially reopen Thursday during an event billed as an evening of remembrance, with speeches from state and local officials.

21 Photos

Mass shootings in 2012

The Post says the city of Aurora expects to distribute nearly 2,000 tickets to victims, emergency responders and hospital workers. Aurora officials say counselors will be made available for anyone needing support during the tours or special event.

Aurora Mayor Steve Hogan, Gov. John Hickenlooper and Cinemark CEO Tim Warner plan to make remarks during the ceremony, the newspaper says, adding that a movie will be shown afterwards.

23 Photos

The Aurora shooting victims

"This is about healing, hope for the future and thanking the literally hundreds of people on the front lines in the immediate aftermath of the shooting," Hogan told the Post. "We're a community that's still working through this."

James Holmes is charged with killing 12 and injuring 70 people on July 20 at the theater in the Denver suburb.

The Batman movie "The Dark Night Rises" was showing at the time.

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Armstrong Admits Doping in Tour, Sources Say

Lance Armstrong today admitted to Oprah Winfrey that he used performance enhancing drugs to win the Tour de France, sources told ABC News.

A government source tells ABC News that Armstrong is now talking with authorities about paying back some of the US Postal Service money from sponsoring his team. He is also talking to authorities about confessing and naming names, giving up others involved in illegal doping. This could result in a reduction of his lifetime ban, according to the source, if Armstrong provides substantial and meaningful information.

Armstrong made the admission in what sources describe as an emotional interview with Winfrey to air on "Oprah's Next Chapter" on Jan. 17.

The 90-minute interview at his home in Austin, Texas, was Armstrong's first since officials stripped him of his world cycling titles in response to doping allegations.

Word of Armstrong's admission comes after a Livestrong official said that Armstrong apologized today to the foundation's staff ahead of his interview.

The disgraced cyclist gathered with about 100 Livestrong Foundation staffers at their Austin headquarters for a meeting that included social workers who deal directly with patients as part of the group's mission to support cancer victims.

Armstrong's "sincere and heartfelt apology" generated lots of tears, spokeswoman Katherine McLane said, adding that he "took responsibility" for the trouble he has caused the foundation.

Riccardo S. Savi/Getty Images|Ray Tamarra/Getty Images

Lance Armstrong Stripped of Tour de France Titles Watch Video

Lance Armstrong Doping Charges: Secret Tapes Watch Video

McLane declined to say whether Armstrong's comments included an admission of doping, just that the cyclist wanted the staff to hear from him in person rather than rely on second-hand accounts.

Armstrong then took questions from the staff.

Armstrong's story has never changed. In front of cameras, microphones, fans, sponsors, cancer survivors -- even under oath -- Lance Armstrong hasn't just denied ever using performance enhancing drugs, he has done so in an indignant, even threatening way.

Armstrong, 41, was stripped of his seven Tour de France titles and banned from the sport for life by the U.S. Anti-Doping Agency in October 2012, after allegations that he benefited from years of systematic doping, using banned substances and receiving illicit blood transfusions.

"Lance Armstrong has no place in cycling and he deserves to be forgotten in cycling," Pat McQuaid, the president of the International Cycling Union, said at a news conference in Switzerland announcing the decision. "This is a landmark day for cycling."

The U.S. Anti-Doping Agency issued a 200-page report Oct. 10 after a wide-scale investigation into Armstrong's alleged use of performance-enhancing substances.

Armstrong won the Tour de France from 1999 to 2005.

According to a source, speaking to ABC News, a representative of Armstrong's once offered to make a donation estimated around $250,000 to the agency, as "60 Minutes Sports" on Showtime first reported.

Lance Armstrong's attorney Tim Herman denied it. "No truth to that story," Herman said. "First Lance heard of it was today. He never made any such contribution or suggestion."

Armstrong, who himself recovered from testicular cancer, created the Lance Armstrong Foundation (now known as the LIVESTRONG Foundation) to help people with cancer cope, as well as foster a community for cancer awareness. Armstrong resigned late last year as chairman of the LIVESTRONG Foundation, which raised millions of dollars in the fight against cancer.

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Is China easing up on local media?

A protester calls for greater media freedom outside the headquarters of Nanfang Media Group in Guangzhou on Jan. 9.

STORY HIGHLIGHTS

• Young: Handling of Southern Weekly row demonstrated tolerant side of new leadership


• Traditional, newer media can serve as tools for achieving goals in China's modernization


• The fight against corruption in China is at the top of the list for incoming leader, Xi Jinping


• Young: Media has also emerged as an important tool for combating other social problems

Editor's note: Doug Young teaches financial journalism at Fudan University in Shanghai and is the author of The Party Line: How the Media Dictates Public Opinion in Modern China published by John Wiley & Sons. He also writes daily on his blog, Young's China Business Blog, commenting on the latest developments in China's fast-moving corporate scene.

Shanghai, China (CNN) -- China's traditional iron-handed approach to the media has taken a surprise turn of tolerance with Beijing's soft handling of a recent dispute with local reporters, in what could well become a more open attitude toward the media under the incoming administration of presumed new President Xi Jinping.

The new openness is being driven in large part by pragmatism, as the government realizes that both traditional and newer media can serve as powerful tools for achieving many of its goals in the country's modernization.

The recent conflict between reporters at the progressive Southern Weekly and local propaganda officials over a censorship incident left many guessing how the government would respond to the first clash of its kind in China for more than 20 years. The result was a surprisingly mild approach, including mediation by a high-level government official and a vague promise for less censorship in the future.

Read: Censorship protest a test for China

The unusually tolerant tack could well reflect a new attitude by Xi and other incoming leaders set to take control of China for the next decade, all of whom have come to realize the media can serve many important functions beyond its traditional role as a propaganda machine.

At the top of Xi's list is the fight against corruption, a problem he has mentioned frequently since taking the helm of the Communist Party last year. The party has tried to tackle the problem for years using its own internal investigations, but progress was slow until recently due to protection many officials received through their own sprawling networks of internal relationships, known locally as guanxi.

Read: Corruption as China's top priority

All that began to change in the last two years with the rapid rise of social media, most notably the Twitter-like microblogs known as Weibo that are now a pervasive part of the Chinese Internet landscape and count hundreds of millions of ordinary Chinese among their users. Those social media have become an important weapon for exposing corruption, allowing thousands of ordinary citizens to pool their resources and build cases against officials they suspect of using their influence for personal gain.

This increasingly sophisticated machine was on prominent display last year in a case involving Yang Dacai, a local official in northwestern Shaanxi province who infuriated the online community by smiling at the site of a horrific accident scene. Netizens quickly turned their outrage into an online investigation, and uncovered photos of him wearing several luxury watches he could hardly afford on his government salary. As a result, the government ultimately opened an investigation into the matter and Yang was sacked from his posts.

In addition to its role in battling corruption, the media has also emerged as an important tool for combating and addressing many of the other social problems that China is facing in its rapid modernization. Barely a week goes by without a report on the latest national food safety scandal or case of illegal pollution in both traditional and social media, with such reports often followed by government investigations.

Beijing leaders have also discovered that the media can also be an important vehicle for improving communication between the government and general public -- something that was a low priority in previous eras when officials only cared about pleasing their higher-up party bosses.

Following a Beijing directive in late 2011, most local government agencies and other organizations have all established microblog accounts, which they use to keep the public informed about their latest activities and seek feedback on upcoming plans. Such input has become a valuable way to temper traditional public mistrust toward the government, which historically didn't make much effort to include the public in any of its internal discussions.

Lastly, the government has also discovered that media, especially social media, can be an effective tool in gauging public opinion on everything from broader national topics like inflation down to very local issues like land redevelopment. Such feedback was difficult to get in the past due to interference by local officials, who tried to filter out or downplay anything with negative overtones and play things up to their own advantage. As a result, central government officials often received incomplete pictures of what was happening in their own country.

With all of these valuable roles to play, the media has become an increasingly important part of Beijing's strategy in executing many of its top priorities.

The government also realizes that a certain degree of openness is critical to letting the media perform many of those roles, which may explain its relatively tolerant approach in the recent Southern Weekly conflict. Such tolerance is likely to continue under Xi's administration, helping to shift more power towards a field of increasingly emboldened reporters at both traditional and new media and away from their traditional propaganda masters.

Follow @CNNOpinion on Twitter.

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The opinions expressed in this commentary are solely those of Doug Young.

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Asian stocks up, Shanghai jumps on regulator comments

HONG KONG: Asian shares were mostly higher on Monday, led by a surge on the Shanghai index after the securities regulator raised hopes for increased foreign investment in China's stock market.

The euro made further gains after upbeat comments last week by the European Central Bank chief, and the yen slid again after reports that the Bank of Japan and government were poised to set a two-per cent inflation target.

Shanghai surged 3.06 per cent, or 68.74 points, to 2,311.74 after the head of China's securities regulator, Guo Shuqing, said the investment quota for foreigners in the domestic equity market could be increased 10-fold.

Hong Kong rose 0.64 per cent, or 149.19 points, to 23,413.26, Seoul added 0.52 per cent, or 10.37 points, to 2,007.04 and Sydney closed up 0.22 per cent, or 10.2 points, at 4,719.7.

But Singapore slipped 0.31 per cent, or 9.91 points, to 3,206.59, pulled down by property stocks after the government introduced new measures at the weekend to cool the local market.

Tokyo was closed for a public holiday.

At a Hong Kong conference on Monday, Guo said at present investment by foreign institutions -- individuals are barred -- accounts for "just 1.5 or 1.6 per cent" of China's A-share market, stock denominated in the domestic yuan currency.

He said the quota could be increased 10-fold in an effort to boost the stock market, without elaborating.

There was no clear lead from Wall Street, where stocks closed in mixed territory on Friday.

The Dow Jones Industrial Average was up 0.13 per cent, the broad-based S&P 500 was flat, while the tech-heavy Nasdaq Composite rose 0.12 per cent.

Investors were looking ahead to a speech by US Federal Reserve chief Ben Bernanke later on Monday.

Minutes from the December meeting of Fed policymakers showed they were divided over how long the central bank should continue asset purchases.

But dealers thought Bernanke was likely to put an end to speculation that US policymakers may end the quantitative-easing programme, with expectations about his comments pushing down the dollar.

"I'd be shocked if he said anything other than they're buying bonds for the long haul," said Davis Scutt, a currency trader at Arab Bank in Sydney.

After tumbling on Friday when the Japanese government unveiled a stimulus package, the yen slid further as reports said the Bank of Japan and the government would jointly set a two-per cent inflation target following pressure from new Prime Minister Shinzo Abe.

The two sides are to finalise a joint statement on monetary measures in time for the central bank's policy meeting on January 21-22, the Asahi Shimbun reported.

A weaker yen helps the country's many exporters, as it makes their products cheaper abroad.

The euro has been surging since Thursday when ECB chief Mario Draghi said there was "a significant improvement in financial market conditions" in the single currency bloc.

On foreign exchange markets in Asian afternoon trade, the euro was at $1.3387, compared to $1.3341 in the US late Friday. The dollar was at 89.61 yen from 89.18 yen, and the euro traded at 119.96 yen from 119.00 yen.

Oil was up. New York's main contract, light sweet crude for delivery in February, rose 69 cents to $94.25 a barrel in the afternoon, and Brent North Sea crude for February delivery gained 43 cents to $111.07.

Gold was at 1,669.90 at 0935 GMT compared with $1,669.80 late Friday.

In other markets:

-- Wellington rose 0.54 per cent, or 22.16 points to 4,153.92.

Fletcher Building added 1.61 per cent to NZ$8.86, Telecom Corp rose 1.08 per cent to NZ$2.335 and The Warehouse gained 0.66 per cent to NZ$3.07.

-- Taipei was flat, edging up 4.82 points to 7,823.97.

Taiwan Semiconductor Manufacturing Co gained 1.0 per cent at NT$102.0 while leading smartphone maker HTC climbed 5.1 per cent to NT$291.0.

-- Manila advanced 0.70 per cent, or 42.15 points, to 6,093.90.

Top-traded Bloomberry Resorts Corp. gained 1.54 per cent to 13.16 pesos while BDO Unibank rose 2.46 per cent to 77 pesos.

- AFP/xq

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United Airlines scheme saves millions on fuel taxes: lawsuit

CHICAGO A transportation agency plans to file a lawsuit Monday alleging that United Airlines is falsely claiming to buy huge amounts of jet fuel out of a small, rural Illinois office that doesn't even have a computer to avoid paying tens of millions of dollars in taxes in Chicago, where the purchases are allegedly being made.

The Regional Transportation Authority alleges United Aviation Fuels Corp., a subsidy of United Airlines, has operated a "sham" office in the DeKalb County community of Sycamore since 2001 after reaching an agreement to pay the town more than $300,000 a year -- a fraction of what it would have owed in sales taxes in Chicago and Cook County.

"The only reason that United Fuels has an office in Sycamore is to attempt to create a sham tax situs (location) for fuel sales in a lower taxing jurisdiction," reads a draft of the lawsuit obtained by The Associated Press.

United officials say they have not seen the lawsuit, but that the Sycamore operation is legal.

The RTA, which contends the office has no computer and is staffed by one person who only works part time, said consultants visited the site on a recent weekday and found it locked with nobody inside. The agency said judging from the few chairs and empty desks seen through a window, there is little, if any, business occurring in the office.

"Whoever is out there is not negotiating hundreds of millions of dollars worth of jet fuel," said Jordan Matyas, the RTA's chief of staff. He said any negotiations for fuel, as well as delivery scheduling, accounting, credit approval and administrative decisions, are being done in the Willis Tower in downtown Chicago, where United is headquartered.

The RTA alleges that American Airlines is engaged in a similar "sham" business out of an office it rents in Sycamore's City Hall. But Matyas said American was not included in the lawsuit because the airline remains in bankruptcy, and that suing American would require litigating the case both in federal bankruptcy court in New York and in Cook County Circuit Court, where the RTA plans to file its suit against United. He added that the RTA does plan to pursue legal action against American at some point.

The two airlines are spending a staggering amount of money on fuel. Based on sales taxes that were paid in Sycamore, the RTA estimates that in 2012 alone, the two airlines spent "approximately $1.2 billion on jet fuel the airlines" for jets at O'Hare, Matyas said in an email, adding that it is unclear how much of that was later sold to other airlines.

United officials said they have not received a copy of the complaint, but "believe that any such suit would be without merit."

"In fact, the operation of our fuel subsidiary in Sycamore has been examined by tax authorities in the past and has been determined to comply with all applicable laws," spokeswoman Megan McCarthy said in an email.

American spokeswoman Mary Frances Fagan said in an email that the airline does not comment on pending litigation but added, "What American is doing is permitted under Illinois law."

Sycamore's city manager, Brian Gregory, declined comment.

The RTA said in a prepared statement that "sales tax dodges" have cost the city of Chicago $133 million in lost sales tax revenue since 2005. They have cost Cook County an additional $60 million and Metra, Pace and the Chicago Transit Authority another $96 million, according to the RTA, which oversees the three agencies and relies on sales tax revenue for much of its funding.

"CTA, Metra and Pace have had to work with constrained budgets and have needed to raise fares and reduce service because the money's just not there," RTA executive director Joe Costello said in the news release. "Now we know why."

The lawsuit is potentially embarrassing for Chicago Mayor Rahm Emanuel, who earlier this year called United's decision to move its corporate headquarters to Chicago "great news for all Chicagoans."

When told of the lawsuit, Emanuel spokeswoman Sarah Hamilton said, "The City has been supportive of efforts in Springfield to ensure corporations pay their fair share, but we have not seen this specific lawsuit and therefore cannot comment on it."

According to the RTA, the total sales tax rate in Sycamore is 9.5 percent, compared to 8 percent in Chicago. But the RTA contends the airlines are getting an even better deal: The two companies have entered 25-year agreements that call for Sycamore to "kick back" most of its share of the sales tax on jet fuel, as much as $14 million a year, in exchange for payments of at least $300,000 a year from each airline.

A document provided by the RTA contends that the agreement with United calls for Sycamore to receive $360,000 to $556,000 between 2003 and 2026.

The lawsuit is part of a larger effort by the RTA to combat similar deals between various communities and companies.

The RTA, the city of Chicago and Cook County in 2011 filed lawsuits against Kankakee and the village of Channahon. They alleged that those communities' tax incentive programs are costing other government agencies millions of dollars, because they enable companies to avoid paying higher sales taxes by moving purchases through satellite offices in areas where the sales tax rates are lower.

According to the RTA's lawsuit against Kankakee and Channahon, the agency is owed at least $100 million in lost revenue. The communities contend their programs are legal.

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Big Winners, Top Moments From the Golden Globes

Let's finally bury this idea that women can't be funny once and for all. Fey and Poehler were undeniably hilarious throughout the Globes, so much so that many fans on Twitter demanded more of them during the ceremony. From their opening bit -- Poehler: "Meryl Streep is not here tonight, she has the flu. And I hear she's amazing in it." -- to their pseudo drunk heckling of best TV comedy actress winner Lena Dunham, they were radiant, energetic, and above all, funny. More please.

Foster made her acceptance of the Cecil B. DeMille lifetime achievement award a coming out, of sorts. She first shocked the audience by leading them to think that she was about to make a huge public statement about her sexuality. Instead, she said she was single, adding "I already did my coming out in the stone age."

"Now, apparently, I'm told that every celebrity is expected to honor the details of their private life with a press conference ... You guys might be surprised, but I'm not Honey Boo Boo child," she said, to a flurry of laughter and applause.

"If you had been a public figure from the time that you were a toddler ... then maybe you too might value privacy above all else," she said. "Privacy."

But Foster did specifically thank her ex-partner Cydney Bernard, with whom she has two kids. Both boys gestured to her from the audience.

She also implied that she was retiring from acting when she said she would not be returning to the Globes stage or any stage. "It's just that from now on, I may be holding a different talking stick," Foster said, bringing many in the audience to tears.

But backstage, Foster clarified to reporters that she was not retiring from acting. "Oh that's so funny," she responded to reporters. "You couldn't drag me away. And I'd like to be directing tomorrow."

It takes a lot to make Hollywood star struck. Bill Clinton did it when he strutted on stage to introduce a clip of "Lincoln," which was up for best drama. He brought the crowd of A-listers to its feet and commended the 16th president. "We're all here tonight because he did it," he said of Lincoln's battle to end slavery.

If there was any doubt that Lena Dunham wasn't Hollywood's next big thing, it was obliterated Sunday night. The star and creator of HBO's "Girls" went home with two awards, best actress in a TV comedy and best TV comedy. Her heartfelt acceptance speech for best actress struck a chord: "This award is for everyone who feels like there wasn't a place for her," she said. "This show made a space for me."

Jessica Chastain won the Globe for best actress in a drama for "Zero Dark Thirty." She offered a moving tribute to director Kathryn Bigelow, the first woman to win a best director Oscar who failed to get a nomination for that award this year, though "ZDT" was up for a slew of other awards, including best picture. "I can't help but compare my character of Maya to you," Chastain said to Bigelow. "When you make a film that allows your character to disobey the conventions of Hollywood, you've done more for women in cinema than you take credit for."

Blame it on nerves, the spirit of spontaneity, or the a-a-a-a-alcohol (apologies to Jamie Foxx), but Jennifer Lawrence's acceptance speech was a tad insulting to a Hollywood icon, if totally hilarious. "Oh what does it say?" she asked, looking at her trophy. "I beat Meryl." She meant Meryl Streep, who was also up for the award.

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Quest: U.S. economy to dominate Davos

The United States and the sorry state of its political and budgetary process will be the center of attention at Davos, writes Quest

STORY HIGHLIGHTS

• Quest: Davos is a chance to see where the political and economic landmines are in 2013


• Quest: People will be speculating about how dysfunctional the U.S. political process has become


• Quest: Davos has been consumed by eurozone sovereign debt crises for three years

Editor's note: Watch Quest Means Business on CNN International, 1900pm GMT weekdays. Quest Means Business is presented by CNN's foremost international business correspondent Richard Quest. Follow him on Twitter.

(CNN) -- It is that time of the year, again. Come January no sooner have the Christmas trees been taken down, as the winter sales are in full vicious flood the world of business start thinking about going to the world economic forum, better known as Davos.

For the past three years Davos has been consumed by the eurozone sovereign debt crises.

As it worsened the speculation became ever more frantic.....Will Greece leave the euro? Will the eurozone even survive? Was this all just a big German trick to run Europe? More extreme, more dramatic, more nonsense.

Can China be the biggest engine of growth for the global economy. Round and round in circles we have gone on these subjects until frankly I did wonder if there was anything else to say short of it's a horrible mess!

This year there is a new bogey man. The US and in particular the sorry state of the country's political and budgetary process will, I have little doubt, be the center of attention.

Read more: More 'cliffs' to come in new Congress

Not just because Congress fluffed its big test on the fiscal cliff, but because in doing so it created many more deadlines, any one of which could be deeply unsettling to global markets... There is the $100 billion budget cutbacks postponed for two months by the recent agreement; postponed to the end of February.

At exactly the same time as the US Treasury's ability to rob Peter to pay Paul on the debt ceiling crises comes to a head.

Read more: Both Obama, GOP set for tough talks ahead

The Treasury's "debt suspension period" is an extraordinary piece of financial chicanery that if we tried it with our credit cards would get us locked up!! Then there is the expiration of the latest continuing resolution, the authority by which congress is spending money.

There is the terrifying prospect that all these budget woes will conflate into one big political fist fight as the US faces cutbacks, default or shutdown!!

I am being alarmist. Most rational people believe that the worst sting will be taken out of this tail....not before we have all been to the edge...and back. And that is what Davos will have on its mind.

People will be speculating about how dysfunctional the US political process has become and is it broken beyond repair (if they are not asking that then they should be...)

They will be pondering which is more serious for risk...the US budget and debt crises or the Eurozone sovereign debt debacle. A classic case of between the devil and the deep blue sea.

The official topic this year is Resilient Dynamism. I have absolutely no idea what this means. None whatsoever. It is another of WEF's ersatz themes dreamt up to stimulate debate in what Martin Sorrell has beautifully terms "davosian language" In short everyone interprets it as they will.

What I will enjoy, as I do every year, is the chance to hear the global players speak and the brightest and best thinkers give us their take on the global problems the atmosphere becomes febrile as the rock-stars of finance and economics give speeches, talk on panels and give insight.

Of course comes of these musings, it never does at Davos. That's not the point. This is a chance to take stock and see where the political and economic landmines are in 2013. I like to think of Davos as the equivalent of Control/Alt/Delete. It allows us to reboot.

We leave at least having an idea of where people stand on the big issues provided you can see through the panegyrics of self congratulatory back slapping that always takes place whenever you get like minded people in one place... And this year, I predict the big issue being discussed in coffee bars, salons and fondue houses will be the United States and its budgetary woes.

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MSF to focus on better organising its delivery of social services

SINGAPORE: Acting Minister for Social and Family Development Chan Chun Sing said his ministry will focus on how to better deliver social services to the people.

This comes after Finance Minister Tharman Shanmugaratnam announced that Budget Day this year will be on February 25.

Mr Chan spoke to reporters on the sidelines of a community event on Sunday morning.

He noted that beyond adjusting and tweaking some of the policies, it is important to assess how these policies can be systematically implemented across the ministry's entire span of social services.

He added that announcements will be made by his ministry in the lead-up to Budget Day.

Mr Chan said: "The focus is not just on the policies alone, of course that we will do, but the focus is also to make sure that we organise ourselves better so that we prepare the ground and set up the social service infrastructure for the many years to come so that in time to come when our social needs increase, when we have more social challenges, we have what we call the social service infrastructure in place to deliver the help to the people in need."

- CNA/fa

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